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If you have previously taken EXMD 609 you must select a topic significantly different from the one you chose for that course. Not more than one student can select any given topic. Topics in italicized red font have already been selected.

  1. Calcium imaging in live animals (Caitlin Anderson)
  2. Genetically-encoded biosensors for intracellular molecules
  3. Chiral chromatography
  4. Purification of subcellular organelles for proteomic analysis
  5. Atomic force microscopy
  6. Stimulated emission depletion (STED) microscopy
  7. Intravital microscopy
  8. Spinning disk confocal microscopy
  9. Multiphoton microscopy
  10. Biological applications of total internal reflection fluorescence microscopy
  11. Applications of Raman scattering microscopy in biomedical research
  12. Lensless on-chip microscopy and its biomedical applications
  13. Biomedical applications of focused ion beam microscopy
  14. Tissue imaging using mass spectrometry
  15. Nano and micro computed tomography
  16. Use of optical tweezers to investigate the properties of molecular motors
  17. Use of surface plasmon resonance for the study of protein-protein interactions
  18. Use of dynamic mass redistribution to evaluate intracellular signaling responses
  19. Generation of genetically engineered animals for food: Methods, controversies and justifications (Claudia Dominici)
  20. Recent progress in in vivo genome editing: Methods, comparative discussion and implications on health research (Lauren Nagel)
  21. Chromatin immunoprecipitation (ChIP) (Herthana Kandasamy)
  22. Tools to investigate miRNA expression and function
  23. Recently-developed methods for the in vitro transfection of cells¬†(excluding calcium phosphate & standard lipofection) (Michael Bruccoleri)
  24. Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase (DamID) (Karla Paez Martinez)
  25. Chromosome conformation capture methodology
  26. The use of transposons to study gene functions
  27. Exome sequencing
  28. Single-cell transcriptomics (Samantha Worme)
  29. In situ sequencing: sequencing genetic material directly from intact tissues
  30. Probes for real-time detection and perturbation of cellular signaling (George Dong)
  31. Bioinformatic methods used to understand gene expression regulation in systems biology approaches
  32. Genome-wide association studies
  33. Identification of protein interactions using phototrapping and photocrosslinking
  34. Use of tandem affinity purification (TAP) for the identification of protein interactions
  35. Determination of the biosynthetic pathways of small peptides
  36. Methods used to study the internalization and fate of cell membrane receptors
  37. Use of NMR in protein characterization
  38. Characterization of proteins by X-ray crystallography
  39. Investigation of protein dynamics using time-resolved X-ray crystallography
  40. Investigation of conformational changes in proteins using ultrafast X-ray free-electron lasers
  41. Determination of protein structure using single-particle cryo-electron microscopy
  42. High throughput methods to identify receptor onists (Ahmed Fouda)
  43. Recent methods for drug delivery and targeting (Yuan Cao)
  44. Gene therapy (Hetaben Patel)
  45. DNA vaccines (Surbhi Kedia)
  46. Dendritic cell vaccines
  47. Oncolytic viruses in cancer therapy (Aymane Deiri)
  48. Use of adoptive cell transfer in biomedical research
  49. Biomedical applications of 3D printing (Jordan Kruisselbrink)
  50. Scaffolds and cells for tissue engineering
  51. Intracellular probes to measure oxidative stress
  52. Methods used to assess angiogenesis (Martin Karam)
  53. Applications of ribozymes in medical research
  54. Biomedical applications of quantum dots
  55. Biomedical applications of magnetic nanoparticles (Rhythm Sharma)
  56. Mapping of neural circuits (Peter Jeon)
  57. Experimental treatment of disease by transplantation of neuronal cells (Sara Sedaghat)
  58. Optogenetics and its applications
  59. Production and applications of organoids (Arash Samiei)
  60. "Disease in a dish" using induced pluripotent stem cells
  61. Organs on chips to model human diseases (Raidan Alyazidi)
  62. Single cell mass cytometry (Joey Heath)
  63. Use of gene drives to target mosquito-borne diseases: methodology, current progress and ethical issues
  64. Epitranscriptome analysis
  65. Biomedical and therapeutic applications of aptamers (Sam Kajjo)
  66. Biomedical and therapeutic applications of focused ultrasound (Taraneh Rafiezadeh)
  67. Targeting RNA using CRISPR (Sahar Mikaeeli)
  68. The use of Genome-wide CRISPR-screening to study cellular functions (Steven Findlay)
  69. In silico approaches to drug development