|
You must choose one of the topics below for your seminar/term paper. If you have previously taken EXMD 610 your topic must differ significantly from the one you chose for that course. Not more than one student can select any given topic. Topics in italicized red font have already been selected.
- Calcium imaging in live animals
- Genetically-encoded biosensors for intracellular molecules
- Chiral chromatography
- Purification of subcellular organelles for proteomic analysis
- Atomic force microscopy
- Stimulated emission depletion (STED) microscopy
- Intravital microscopy
- Spinning disk confocal microscopy
- Multiphoton microscopy
- Biological applications of total internal reflection fluorescence microscopy
- Applications of Raman scattering microscopy in biomedical research
- Lensless on-chip microscopy and its biomedical applications
- Biomedical applications of focused ion beam microscopy
- Tissue imaging using mass spectrometry
- Nano and micro computed tomography
- Use of optical tweezers to investigate the properties of molecular motors
- Use of surface plasmon resonance for the study of protein-protein interactions
- Use of dynamic mass redistribution to evaluate intracellular signaling responses
- Generation of genetically engineered animals for food: Methods, controversies and justifications (Luz Ramos Ballesteros)
- Recent progress in in vivo genome editing: Methods, comparative discussion and implications on health research (Owen Dunkley)
- Chromatin immunoprecipitation (ChIP) (Michael Gong)
- Tools to investigate miRNA expression and function
- Recently-developed methods for the in vitro transfection of cells (excluding calcium phosphate & standard lipofection) (Harvey Li)
- Identification of in vivo DNA targets of chromatin proteins using tethered Dam methyltransferase (DamID)
- Chromosome conformation capture methodology
- The use of transposons to study gene functions (Sarah Yull)
- Exome sequencing
- Single-cell transcriptomics
- In situ sequencing: sequencing genetic material directly from intact tissues (Sahar Mikaeeli)
- Probes for real-time detection and perturbation of cellular signaling
- Bioinformatic methods used to understand gene expression regulation in systems biology approaches
- Genome-wide association studies
- Identification of protein interactions using phototrapping and photocrosslinking
- Use of tandem affinity purification (TAP) for the identification of protein interactions
- Determination of the biosynthetic pathways of small peptides
- Methods used to study the internalization and fate of cell membrane receptors
- Use of NMR in protein characterization
- Characterization of proteins by X-ray crystallography
- Investigation of protein dynamics using time-resolved X-ray crystallography
- Investigation of conformational changes in proteins using ultrafast X-ray free-electron lasers
- Determination of protein structure using single-particle cryo-electron microscopy
- High throughput methods to identify receptor antagonists
- Drug development using combinatorial chemistry
- Carbon nanotubes and their potential use for drug delivery
- New methods for drug delivery and targeting (excluding carbon nanotubes) (Jasman Jasman)
- Gene therapy (Sheren Samuel)
- DNA vaccines (Xavier Allard-Chamard)
- Dendritic cell vaccines (Yujian Yang)
- Oncolytic viruses in cancer therapy (Michael Bruccoleri)
- Use of adoptive cell transfer in biomedical research (Noah Cohen)
- Biomedical applications of 3D printing
- Scaffolds and cells for tissue engineering (Karim Jabbour)
- Intracellular probes to measure oxidative stress (Cristian Galindo)
- Methods used to assess angiogenesis
- Applications of ribozymes in medical research
- Biomedical applications of quantum dots
- Biomedical applications of magnetic nanoparticles (Pierre-Guy Millette)
- Mapping of neural circuits
- Experimental treatment of disease by transplantation of neuronal cells
- Optogenetics and its applications (Dorsa Majdpour)
- Living cell microarrays
- Production and applications of organoids (Wael Abdelmageed)
- "Disease in a dish" using induced pluripotent stem cells (Marie-Hélène Godin Pagé)
- Organs on chips to model human diseases
- Single cell mass cytometry (Chad Poloni)
- Use of gene drives to target mosquito-borne diseases: methodology, current progress and ethical issues
- Epitranscriptome analysis
- Biomedical and therapeutic applications of aptamers
- Biomedical and therapeutic applications of focused ultrasound
- Targeting RNA using CRISPR (Sai Priya Anand)
- The use of Genome-wide CRISPR-screening to study cellular functions
- In silico approaches to drug development
|